12x12 Hemostatic Dressing

At Its Best
When Bleeding
Is At Its Worst.®

A Breakthrough In Controlling Profuse Bleeds

QuikClot Control+® is the first and only hemostatic dressing indicated for temporary control of internal organ space bleeding for patients displaying class III or class IV bleeding. A new option that can be delivered quickly, easily and reliably to offer effective, safe and efficient performance in the worst bleeds.

Another Proven Technology From A Recognized Innovator

QuikClot Control+ is just the latest innovation from Z-Medica®. Since 2002, the company has been developing and delivering superior hemostatic devices to healthcare providers, military personnel, first responders, and consumers around the world.  

Medical Cross

 

Efficacy And Safety You Can Believe In

QuikClot Control+ is impregnated with kaolin, a naturally occurring, inorganic mineral that accelerates the body’s natural clotting process.1,2 It’s the same active ingredient used in QuikClot Combat Gauze®. Because kaolin contains no animal or human proteins, no thrombin, fibrinogen, botanicals, or shellfish products, there is no risk of allergic responses.1-3 Biocompatibility studies have shown that it is safe and has no negative effect on tissues.3 Integrated double X-ray indicators facilitate detection and removal, reducing the risk of lost or retained product.

Alarm Clock

 

Efficiency When It Counts

The sooner you can control bleeding, the sooner you can begin treating the cause. QuikClot Control+ enables you to combine conventional packing and pressure with the proven hemostatic performance of kaolin. Because it’s applied like standard gauze, QuikClot Control+ is completely intuitive, allowing you to follow established protocols while accelerating the path to hemostasis. The gauze-based format blends familiarity and ease-of-use with proven efficacy.3,4

  • Ready to use out of the package
  • No mixing, preparation, or defrosting required
  • Apply like a standard dressing or sponge — no learning curve
  • Pliable, moldable, shapeable — can be used flat, rolled, or wadded as needed
  • Available in a range of sizes that can be tailored for usage

Bar Graph Rising

 

An Economical Solution

Reducing bleeding saves more than lives; it can also represent significant cost savings. Studies have shown that bleeding-related transfusions5-7 or complications7 due to significant blood loss lead to:

  • Increased risk of infection5,6
  • Longer ICU stay6,7
  • Longer hospital stay6,7
  • Higher total hospital costs6,7
  • Increased postoperative morbidity and mortality6

Koko KR, McCauley BM, Gaughan JP, et al. Kaolin-based hemostatic dressing improves hemorrhage control from a penetrating inferior vena cava injury in coagulopathic swine. J Trauma Acute Care Surg. 2017;83(1):71-76.

 

In a preclinical study of 12 swine, significantly less blood loss after packing was seen with QuikClot Control+ (651+/-179 ml) compared to standard packing (1073+/-342 ml) (p≤0.05).4

QuikClot Control+ (n=6) was compared to standard laparotomy pads (n=6) in packing a penetrating Retrohepatic Vena Cava (RVC) injury for 6 hours in hypothermic coagulopathic swine. The study showed the benefits of using QuikClot Control+ and the “results demonstrate that the use of this new hemostatic kaolin-based dressing improved hemorrhage control and significantly decreased blood loss in this penetrating RIVC model.”4

  1. All animals treated with QuikClot Control+ (100%, 6/6) survived, compared to 83% (5/6) of animals treated with standard packing.
  2. Significantly less blood loss after packing was seen with QuikClot Control+ (651+/-180 ml) compared to standard packing (1073+/-342 ml) (p≤0.05).
  3. Over the course of 6 hours, the authors “observed an upward trend in heart rate in the laparotomy sponge group and a downward trend in the kaolin based dressing group, indicating that there was likely less ongoing hemorrhage in the kaolin based experimental group.”4

magnifying glass  PRECLINICAL DATA

Accelerating The Body’s Natural Clotting Cascade

Kaolin works on contact with blood to immediately initiate the clotting process by activating factor XII.2 This reaction leads to the transformation of factor XII to its activated form XIIa, which instigates the rest of the coagulation cascade.8

Clotting Cascade

Chemical Formula

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  Show References

REFERENCES: 1. Trabattoni D, Montorsi P, Fabbiocchi F, Lualdi A, Gatto P, Bartorelli AL. A new kaolin-based haemostatic bandage compared with manual compression for bleeding control after percutaneous coronary procedures. Eur Radiol. 2011;21:1687-1691. 2. Lamb KM, Pitcher HT, Cavarocchi NC, Hirose H. Vascular site hemostasis in percutaneous extracorporeal membrane oxygenation therapy. Open Cardiovasc Thorac Surg J. 2012;5:8-10. 3. Data on File. 4. Koko KR, McCauley BM, Gaughan JP, et al. Kaolin-based hemostatic dressing improves hemorrhage control from a penetrating inferior vena cava injury in coagulopathic swine. J Trauma Acute Care Surg. 2017;83(1):71-76. 5. Carson JL, Altman DG, Duff A, et al. Risk of bacterial infection associated with allogenic blood transfusion among patients undergoing hip fracture repair. Transfusion. 1999 Jul; 39(7):694-700. 6. Morton J, Anastassopoulos KP, Patel ST, et al. Frequency and outcomes of blood products transfusion across procedures and clinical conditions warranting inpatient care: an analysis of the 2004 healthcare cost and utilization project nationwide inpatient sample database. Am J Med Qual. 2010 Jul/Aug; 25(4):289-296. 7. Stokes ME, Ye X, Shah M, et al. Impact of bleeding-related complications and/ or blood product transfusions on hospital costs in inpatient surgical patients. BMC Health Serv Res. 2011; 11:135. 8. Dee KC, Puleo DA, Bizios R. An Introduction to Tissue-Biomaterial Interactions. Hoboken, NJ: Wiley & Sons; 2002. 

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